Most children who have hypoparathyroidism occurs in the first years of life, it has autoimmune nature. Some patients with acquired hypoparathyroidism were found antibodies to the extracellular domain of a calcium receptor.
Pediatric rheumatology, the health of the baby. Organization of pediatric rheumatologists.
In children with a birth weight of 1000 g and a gestation 26-28 weeks and below at the lack of prevention of developing severe bone demineralization, which in some children may lead to pathological fractures.
Osteopenia is a pathology characterized by low bone mass in a particular age.
A child with juvenile rheumatoid arthritis is in the group of high risk, nedostaje adequate bone mass in postpubertatne period. Introduction dual-energy x-ray absorptiometry allowed us to assess the degree of osteopenia in these children led to the realization of the scale of the problem. When this disease affects the peripheral skeleton, and trabecular bone of the spine, but the first in more. Osteopenia in children is correlated with activity of the disease and its severity. Other associated factors are reduced physical activity, immobility, reduced sun exposure and decreased calcium intake and vitamin D from food. It is known that peak bone mass is usually achieved in adolescence, which is important to minimize the risk of osteoporosis and fractures in the future. Often in juvenile rheumatoid arthritis bone density in puberty does not reach the anticipated increase. In patients with severe polyarthritis discovered osteopenic axial lumbar spine and femoral neck. In a two-year prospective controlled study of early juvenile idiopathic arthritis, including JRA, psoriatic arthritis and ankylosing spondylitis, there was a slight reduction in the increase of bone mass, bone remodeling, and total lean mass.
The treatment of this disease is quite complicated. It can heal not in every clinic. If you are not satisfied with the results, you should pay attention to the treatment in Israel, for example on the company Adar medical. The details can be found on its website adarmedic.ru.
Therapy osteopenia in children includes strengthening exercises, proper nutrition, calcium and vitamin D as well, and this is key, sufficient suppression of disease activity (systemic inflammation). In his early works demonstrated the effectiveness of bisphosphonates, although their use had adverse effects. To increase consumption of dietary calcium may be recommended for active learning. In addition to General osteopenia in the affected joints in the early stages are defined areas of subchondral demineralization. Regular monitoring is recommended densitometry.
The local disturbance of growth in juvenile arthritis in children occurs as a result of inflammation and a concomitant increase in vascularization that may lead either to excessively rapid growth or lack of growth of the affected bone. Detecting local disorders of growth – an important element of diagnosis of juvenile arthritis.
The term "vasculitis" refers to a large group of diseases that are partially similar to the diffuse connective tissue diseases.
Causes immune-mediated mechanisms of inflammation of the blood vessels are infection, drugs, malignancies. For symptoms of vasculitis in children characterized hemorrhagic palpable rash in the absence of thrombocytopenia, arthritis, fever, myalgia, fatigue, decrease or pathological increase in body weight, increased ESR. Besides the skin affects the joints, lungs, kidneys, CNS.
Disease Henoch-Schonlein Purpura
Hemorrhagic vasculitis in children of school age appears hemorrhagic rash, mainly on the legs and buttocks. Infantile hemorrhagic edema, which occurs in children up to 3 years, similar in something with hemorrhagic vasculitis, but has some differences. The rash of it are clearly delineated and hemorrhagic papules and plaques located on the trunk and extremities. In contrast to hemorrhagic vasculitis, observed eruptions on the face, but internal organs are not affected. In the differential diagnosis of hemorrhagic vasculitis include infection with hemorrhagic rashes: meningococcal sepsis, Rocky mountain spotted fever, hemorrhagic rash, caused by enteroviruses, rheumatoid arthritis, other vasculitides in children.
The clinical picture of Kawasaki disease consists of cutaneous and waconah symptoms of vasculitis in children. Polymorphous skin rash — blisters, spots, papules, and morbilliform erythema, plaques on the trunk and extremities. The rash starts in the groin creases that pathognomonic for this disease. Another characteristic symptom of vasculitis in children — swelling and peeling of the hands and feet, but they appear later. The typical lesions of mucous membranes, conjunctivitis, is usually not spectacular limb of the cornea, and plaques on the mucosa of the tongue ("white strawberry tongue"), which are exfoliated. Language becomes bright, with protruding papillae ("strawberry tongue"). Histological changes in the skin are nonspecific and do not facilitate the differential diagnosis with viral or bacterial asanteman and drug rashes.
A systemic disease characterized by ulceration of the oral mucosa, genital, eye lesions (uveitis, recurrent iridocyclitis). In 98% of cases observed recurrent aphthous stomatitis is the most common symptom of vasculitis in children. Ulceration on the genitals resemble aphthae. In men they are located on the penis and the scrotum. In women, rashes in the genital area is especially painful. In addition, lesions of the skin include folliculitis, hemorrhagic vasculitis, nodular erythema, pustules in the field of venepuncture and minor injuries. The differential diagnosis of changes in the mucosa of the oral cavity includes aphthous stomatitis, herpes, and relatively rare syndromes with a lesion of the mucous membranes and the eyes, such as the MAGIC syndrome (an acronym for "mouth and genital ulcers with inflamed cartilage" — ulceration of the mucous membrane of the mouth, genitals and inflammation of cartilage), skin Biopsy reveals lakokrasochnyi or lymphocytic vasculitis. The defeat of the oral mucosa is eliminated medicinal products for sucking or chewing include corticosteroids, antihistamines, antibiotics and analgesics.
It is important to discuss school problems with patients, family and, if necessary, representatives of the school.
According to doctors, 34-year-old man, whose name was not disclosed, remained only 100 orgasms before erection will leave him forever, writes . The reason is a rare disorder - whenever ejaculation happens, the penis formed scar tissue due to an autoimmune reaction (the body attacks healthy tissues, destroying them). .
Central rheumatic disease in children today – juvenile idiopathic (or rheumatoid, as it was called earlier) arthritis. Other diseases or rarer or less dangerous.